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Elise Arbeille for help with ISHs of spinal cord sections

Pawson T, Scott JD: Signaling through scaffold, 24276-84-4 manufacturer anchoring, and adaptor proteins. Nat Rev Neurosci 2007, 8:331? FH wrote the manuscript with proofreading by FM. 7. Received: 1 July 2014 Accepted: 4 July4.5.23.14. EMBO J 2004, 23:3803?814.Ing interests. Kanning KC, Kaplan A, Henderson CE: Motor neuron diversity in Bafetinib development and disease.17. J Neurosci 2011, 31:11144?1158. 3. Postigo A,

Calella AM, Fritzsch B, Knipper M, Katz D, Eilers A, Schimmang T, Lewin GR, Klein R, Minichiello L: Distinct requirements for TrkB and TrkC signaling in target innervation by sensory neurons. Mol Cell 2001, 7:1293?306.9. 2. The contributions of the Region Provence Alpes C es d'Azur and Aix-Marseille Universit?for the IBDM animal facility, and of the France-BioImaging/PICsL infrastructure (ANR-10-INSB-04-01) for the imaging facility are also acknowledged.15.

Final approval was given by all authors.FH, NC, BH, FL and VA-G performed the experiments.18. Curr Top Dev Biol 2009, 87:119?48. Work in the Maina lab by FM was supported by FRM, AFM, FdF, ARC, Fondation Bettencourt-Schueller and INCa (Institut National du Cancer). Science 1997, 278:2075?080. Maina F, Pante G, Helmbacher F, Andres R, Porthin A, Davies AM, Ponzetto C, Klein R: Coupling Met to specific pathways results in distinct developmental outcomes.6. Acknowledgements We thank Chris Henderson for invaluable intellectual support; Ruediger Klein for supporting this study in its early stages and for valuable comments on the manuscript, and former members of his laboratory for insightful discussion;

Elise Arbeille for help with ISHs of spinal cord sections; Sylvie Richelme for technical help; Virginia Girod-David and Leo Jullien for excellent help with mouse husbandry at the IBDM; and Angela Zimmermann for comments on the manuscript.21.References 1.Lamballe F, Genestine M, Caruso N, Arce V, Richelme S, Helmbacher F, Maina F: Pool-specific regulation of motor neuron survival by neurotrophic support. Polleux F,

Ince-Dunn G, Ghosh A: Transcriptional regulation of vertebrate axon guidance and synapse formation. Encinas M, Tansey MG, Tsui-Pierchala BA, Comella JX, Milbrandt J, Johnson EM Jr: c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3 K)-dependent pathway.20.19. Medina DL, Sciarretta C, Calella AM, Von Bohlen Und Halbach O, Unsicker K, Minichiello L:

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